NEW YORK-- December 02, 2022 -- Timed to World AIDS Day, Sermo, a physician-first online community and leader in global HCP insights, released a new survey that found 46% of general care physicians including PCPs, OB-GYNs, and pediatric physicians, reported they feel they do not have enough knowledge about currently approved PrEP medication options to prescribe them to patients. Whereas 98% of infectious disease specialists reported they felt they have enough knowledge about PrEP medications signaling a need for further education from industry stakeholders for noninfectious disease specialists. An important area of opportunity as patients who are likely good candidates for PrEP often go to a PCP instead of seeking out an infectious disease specialist.

The cost of PrEP continues to be a driving factor for patients’ decision to decline treatment in the U.S. as reported by 26% of surveyed physicians. However, PrEP is fully covered in most instances when a patient has private insurance, highlighting another opportunity to further educate patients and providers via patient support and financial assistance programs. Despite PrEP private insurance coverage, young adults 26 years old and under face insurance barriers to accessing PrEP. 23% of surveyed physicians said they don’t know of any resources to help patients on their parent's insurance who want to access PrEP but don’t want their parents to find out. This number declined to 16% when surveying just infectious disease specialists, suggesting an area of opportunity for wider outreach among patient support and financial assistance programs to help this patient population.

Concerns about the cost being the driving factor for patients declining PrEP are lower in Europe than in the U.S. When comparing physician experiences, cost was the number one driver of patients declining PrEP treatment compared to the number three reason in the EU5. The rest of the world followed the U.S. sentiment of cost being the leading reason patients decline PrEP. In Europe, physicians reported the top reason patients declined PrEP treatment is planning to take other preventative measures (27%), followed by stigma (24%), and then cost (20%).

PrEP Adoption Faces Challenges on Multiple Fronts Beyond Cost and Education:

· PrEP isn’t top-of-mind for most patients: only 16% of surveyed physicians reported that patients often proactively asked them for PrEP.
· Patients struggle to maintain adherence to PrEP: 70% of surveyed physicians reported that patients often or sometimes have a hard time adhering to the once-a-day pill schedule of taking PrEP.
· Misinformation about how PrEP works persists as 49% of surveyed physicians reported hearing misinformation about the treatment from patients in their practices.
· When asked the most common misinformation they hear in their practices, PrEP is only for men who have sex with other men is what they heard most often as reported by 63% of physicians. This is in contradiction with the reality that an average of 22% of new HIV diagnoses each year are from heterosexual contact.

“HIV is 100% preventable. Education for both providers and patients is critical in making more progress against the HIV/AIDS epidemic,” says Dr. Claudia Martorell, an Infectious Disease Specialist and Sermo Medical Advisory Board Member. “Education, along with improved insurance coverage, increased medication awareness, better access for at-risk populations, and decreasing stigma around HIV infection all support our ability to do a better job in ending the epidemic.”

Cost & Adherence Keep HIV Patients From Successful Treatment Regiments:
Similar to concerns about the cost of PrEP, affordability is the key treatment attribute that is most important to physicians when recommending an HIV medication to a patient (17%) followed by fewer side effects (15%), and less medication to take each day (13%). In addition, physicians reported adherence is another key barrier to HIV treatment as more than half (56%) of physicians reported that patients they are treating for HIV/AIDS have a difficult time following a strict medication adherence program. Interest in longer-lasting injectable medications is likely to be high among HIV patients, as 48% of surveyed physicians reported that patients simply forgetting to take their medication is the top reason patients didn’t adhere to treatment plans. Multidrug-resistant HIV is also a huge concern for physicians as nearly half (43%) reported treating patients with these issues.

This survey was fielded as part of Sermo’s ongoing Barometer survey. The survey included more than 600 global physicians who were surveyed between November 2nd - 14th, 2022. To explore more findings, visit